Selected Publications

Ambrose, Z., and KewalRamani, V.N.  (2008)  Of mice and monkeys: New advances in animal models to study HIV-1 therapy and prophylaxis.  Future HIV Ther. 2: 363-373.
[Abstract]     [Full-text PDF article]

Ambrose, Z., Compton, L., Piatak, M., Jr., Lu, D., Alvord, W.G., Lubomirski, M.S., Hildreth, J.E.K., Lifson, J.D., Miller, C.J., and KewalRamani, V.N.  (2008)  Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges.  J. Virol. 82: 6591-6599.
[Abstract]     [Full-text PDF article]

Mulky, A., Cohen, T.V., Kozlov, S.V., Korbei, B., Foisner, R., Stewart, C.L., and KewalRamani, V.N.  (2008)  The LEM domain proteins emerin and LAP2a are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections.  J. Virol. 82: 5860-5868.     [Abstract]     [Full-text PDF article]

Ambrose, Z., Palmer, S., Boltz, V.F., Kearney, M., Larsen, K., Polacino, P., Flanary, L., Oswald, K., Piatak, M., Jr., Smedley, J., Shao, W., Bischofberger, N., Maldarelli, F., Kimata, J.T., Mellors, J.W., Hu, S.-L., Coffin, J.M., Lifson, J.D., and KewalRamani, V.N.  (2007)  Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy.  J. Virol. 81: 12145-12155.
[Abstract]     [Full-text PDF article]

Ambrose, Z., KewalRamani, V.N., Bieniasz, P.D., and Hatziioannou, T.  (2007)  HIV/AIDS: In search of an animal model.  Trends Biotechnol. 25: 333-337.
[Abstract]     [Full-text PDF article]

Wang, J.-H., Janas, A.M., Olson, W.J., KewalRamani, V.N., and Wu, L.  (2007)  CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1.  J. Virol. 81: 2497-2507.     [Abstract]     [Full-text PDF article]

Wu, L., and KewalRamani, V.N.  (2006)  Dendritic-cell interactions with HIV: Infection and viral dissemination.  Nat. Rev. Immun. 6: 859-868.     [Abstract]     [Full-text PDF article]

Ambrose, Z., Julias, J.G., KewalRamani, V.N., and Hughes, S.H.  (2006)  The level of reverse transcriptase (RT) in human immunodeficiency virus type 1 particles affects susceptibility to nonnucleoside RT inhibitors but not to lamivudine.  J. Virol. 80: 2578-2581.
[Abstract]     [Full-text PDF article]

Sun, J., Soos, T., KewalRamani, V.N., Osiecki, K., Zheng, J.H., Falkin, L., Santambrogio, L., Littman, D.R., and Goldstein, H.  (2006)  CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate.  J. Virol. 80: 1850-1862.     [Abstract]     [Full-text PDF article]

Garcia-Pineres, A.J., Hildesheim, A., Trivett, M., Williams, M., Wu, L., KewalRamani, V.N., and Pinto, L.A.  (2006)  Role of DC-SIGN in the activation of dendritic cells by HPV-16 L1 virus-like particle vaccine.  Eur. J. Immunol. 36: 437-445.
[Abstract]     [Full-text PDF article]

VanCompernolle, S.E., Taylor, R.J., Oswald-Richter, K., Jiang, J., Youree, B.E., Bowie, J.H., Tyler, M.J., Conlon, J.M., Wade, D., Aiken, C., Dermody, T.S., KewalRamani, V.N., Rollins-Smith, L.A., and Unutmaz, D.  (2005)  Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells.  J. Virol. 79: 11598-11606.     [Abstract]     [Full-text PDF article]

Ambrose, Z., Boltz, V., Palmer, S., Coffin, J.M., Hughes, S.H., and KewalRamani, V.N.  (2004)  In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques.  J. Virol. 78: 13553-13561.     [Abstract]     [Full-text PDF article]

Baumann, J.G., Unutmaz, D., Miller, M.D., Breun, S.K.J., Grill, S.M., Mirro, J., Littman, D.R., Rein, A., and KewalRamani, V.N.  (2004)  Murine T cells potently restrict human immunodeficiency virus infection.  J. Virol. 78: 12537-12547.
[Abstract]     [Full-text PDF article]

Lee, K., and KewalRamani, V.N.  (2004)  In defense of the cell: TRIM5a interception of mammalian retroviruses.  Proc. Natl. Acad. Sci. USA 101: 10496-10497(Epub).
[Abstract]     [Full-text PDF article]

Wu, L., Martin, T.D., Han, Y.-C., Breun, S.K.J., and KewalRamani, V.N.  (2004)  Trans-dominant cellular inhibition of DC-SIGN-mediated HIV-1 transmission.  Retrovirology 1: 14 (Epub).     [Full-text HTML article]     [Full-text PDF article]

Wu, L., Martin, T.D., Carrington, M., and KewalRamani, V.N.  (2004)  Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission.  Virology 318: 17-23.
[Abstract]     [Full-text PDF article]

KewalRamani, V.N., and Coffin, J.M.  (2003)  Weapons of mutational destruction.  Science 301: 923-925.      [Summary]     [Full-text PDF article]

McDonald, D., Wu, L., Bohks, S.M., KewalRamani, V.N., Unutmaz, D., and Hope, T.J.  (2003)  Recruitment of HIV and its receptors to dendritic cell-T cell junctions.  Science 300: 1295-1297.
[Abstract]     [Full-text PDF article]

Wu, L., Martin, T.D., Vazeux, R., Unutmaz, D., and KewalRamani, V.N.  (2002)  Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission.  J. Virol. 76: 5905-5914.
[Abstract]     [Full-text PDF article]

Wu, L., Bashirova, A.A., Martin, T.D., Villamide, L., Mehlhop, E., Chertov, A.O., Unutmaz, D., Pope, M., Carrington, M., and KewalRamani, V.N.  (2002)  Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN.  Proc. Natl. Acad. Sci. USA 99:1568-1573.     [Abstract]     [Full-text PDF article]

Bashirova, A.A., Geijtenbeek, T.B., van Duijnhoven, G.C., van Vliet, S.J., Eilering, J.B., Martin, M.P., Wu, L., Martin, T.D., Viebig, N., Knolle, P.A., KewalRamani, V.N., van Kooyk, Y., and Carrington, M.  (2001)  A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.  J. Exp. Med. 193:671-678.     [Abstract]     [Full-text PDF article]

Geijtenbeek, T.B., Kwon, D.S., Torensma, R., van Vliet, S.J., van Duijnhoven, G.C., Middel, J., Cornelissen, I.L., Nottet, H.S., KewalRamani, V.N., Littman, D.R., Figdor, C.G., and van Kooyk, Y.  (2000)  DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells.  Cell 100: 587-597.     [Abstract]     [Full-text PDF article]

Unutmaz, D., KewalRamani, V.N., Marmon, S., and Littman, D.R.  (1999)  Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes.  J. Exp. Med. 189: 1735-1746.     [Abstract]     [Full-text PDF article*]

Garber, M.E., Wei, P., KewalRamani, V.N., Mayall, T.P., Herrmann, C.H., Rice, A.P., Littman, D.R., and Jones, K.A.  (1998)  The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein.  Genes Dev. 12: 3512-3527.     [Abstract]     [Full-text PDF article^§]

Deng, H.-K., Unutmaz, D., KewalRamani, V.N., and Littman, D.R.  (1997)  Expression cloning of new receptors used by simian and human immunodeficiency viruses.  Nature 388: 296-300.     [Abstract]

KewalRamani, V.N., and Emerman, M.  (1996)  Vpx association with mature core structures of HIV-2.  Virology 218: 159-168.     [Abstract]     [Full-text PDF article]

KewalRamani, V.N., Panganiban, A.T., and Emerman, M.  (1992)  Spleen necrosis virus, an avian immunosuppressive retrovirus, shares a receptor with the type D simian retroviruses.  J. Virol. 66: 3026-3031.     [Abstract]

* Reproduced from The Journal of Experimental Medicine, 1999, Vol. 189, pp. 1735-1746 by copyright permission of The Rockefeller University Press.

^§ Permission was granted from Cold Spring Harbor Laboratory Press to copy this PDF article and link it directly on this website.