Structure of HIV-1 reverse transcriptase (RT)/double-stranded (ds) DNA complex (collaboration with Edward Arnold, CABM, Rutgers University):

Selected pictures of HIV-1 RT by Kalyan Das, based on structural studies at Edward Arnold's lab:

	Three major types of HIV-1 RT structures
	Movement of p66-thumb subdomain with the binding of DNA or a nonnucleoside RT inhibitor (NNRTI) to HIV-1 RT
	Crystal structure of HIV-1 RT/dsDNA complex
	Locations of important active sites in HIV-1 RT/dsDNA structure
	Locations of nucleoside RT inhibitor (NRTI) mutation sites in HIV-1 RT/dsDNA structure
	Commonly occurring drug-resistance sites in HIV-1 RT
	Binding modes of NNRTIs to HIV-1 RT
	Comparison of structures of wild-type and Tyr181Cys mutant RT TIBO complexes