Selected Publications

Li, K., Zhang, S., Kronqvist, M., Wallin, M., Ekström, M., Derse, D., and Garoff, H.  (2008)  Intersubunit disulfide isomerization controls membrane fusion of human T-cell leukemia virus Env.  J. Virol. 82: 7135-7143.     [Abstract]     [Full-text PDF article]

Rulli, S.J., Jr., Mirro, J., Hill, S.A., Lloyd, P., Gorelick, R.J., Coffin, J.M., Derse, D., and Rein, A.  (2008)  Interactions of murine APOBEC3 and human APOBEC3G with murine leukemia viruses.  J. Virol. 82: 6566-6575.
[Abstract]     [Full-text PDF article]

Derse, D.  (2007)  Role of mouse APOBEC3 in the restriction of mouse mammary tumor virus replication in vivo.  Future HIV Ther. 1: 149-152.
[Summary]     [Full-text PDF article]

Heidecker, G., Lloyd, P.A., Soheilian, F., Nagashima, K., and Derse, D.  (2007)  The role of WWP1-Gag interaction and Gag ubiquitination in assembly and release of human T-cell leukemia virus type 1.  J. Virol. 81: 9769-9777.     [Abstract]     [Full-text PDF article]

Derse, D., Crise, B., Li, Y., Princler, G., Lum, N., Stewart, C., McGrath, C.F., Hughes, S.H., Munroe, D.J., and Wu, X.  (2007)  Human T-cell leukemia virus type 1 integration target sites in the human genome: Comparison with those of other retroviruses.  J. Virol. 81: 6731-6741.     [Abstract]     [Full-text PDF article]

Mitchell, M.S., Bodine, E.T., Hill, S.A., Princler, G., Lloyd, P., Mitsuya, H., Matsuoka, M., and Derse, D.  (2007)  Phenotypic and genotypic comparison of human T-cell leukemia virus type 1 reverse transcriptase from infected T-cell lines and patient samples.  J. Virol. 81: 4422-4428.     [Abstract]     [Full-text PDF article]

Derse, D., Hill, S.A., Princler, G., Lloyd, P., and Heidecker, G.  (2007)  Resistance of human T cell leukemia virus type 1 to APOBEC3G restriction is mediated by elements in nucleocapsid.  Proc. Nat. Acad. Sci. USA 104: 2915-2920.
[Abstract]     [Full-text PDF article]

Mazurov, D., Heidecker, G., and Derse, D.  (2007)  The inner loop of tetraspanins CD82 and CD81 mediates interactions with human T cell lymphotrophic virus type 1 Gag protein.  J. Biol. Chem. 282: 3896-3903.      [Abstract]     [Full-text PDF article]

Wencker, M., Sausse, C., Derse, D., Gazzolo, L., and Dodon, M.D.  (2007)  Human T-cell leukemia virus type 1 Tax protein down-regulates pre-T-cell receptor alpha gene transcription in human immature thymocytes.  J. Virol. 81: 301-308.
[Abstract]     [Full-text PDF article]

Zhang, F., Hatziioannou, T., Perez-Caballero, D., Derse, D., and Bieniasz, P.D.  (2006)  Antiretroviral potential of human tripartite motif-5 and related proteins.  Virology 353: 396-409.     [Abstract]     [Full-text PDF article]

Derse, D.  (2006)  HTLV tax tails.  Blood 107: 1740-1741.     [Full-text PDF article]

Mazurov, D., Heidecker, G., and Derse, D.  (2006)  HTLV-1 Gag protein associates with CD82 tetraspanin microdomains at the plasma membrane.  Virology 346: 194-204.
[Abstract]     [Full-text PDF article]

Mitchell, M., Tözsér, J., Princler, G.L., Lloyd, P.A., Auth, A. and Derse, D.  (2006)  Synthesis, processing, and composition of the virion-associated HTLV-1 reverse transcriptase.  J. Biol. Chem. 281: 3964-3971.      [Abstract]     [Full-text PDF article]

Derse, D., Heidecker, G., Mitchell, M., Hill, S., Lloyd, P., and Princler, G.  (2004)  Infectious transmission and replication of human T-cell leukemia virus type 1.  Front. Biosci. 9: 2495-2499.     [Abstract]     [Full-text PDF article]

Heidecker, G., Lloyd, P.A., Fox, K., Nagashima, K., and Derse, D.  (2004)  Late assembly motifs of human T-cell leukemia virus type 1 and their relative roles in particle release.  J. Virol. 78: 6636-6648.     [Abstract]     [Full-text PDF article]

Liao, H.-J., Baker, C.C., Princler, G.L., and Derse, D.  (2004)  cis-Acting and trans-acting modulation of equine infectious anemia virus alternative RNA splicing.  Virology 323: 131-140.     [Abstract]     [Full-text PDF article]

Nicot, C., Dundr, M., Johnson, J.M., Fullen, J.R., Alonzo, N., Fukumoto, R., Princler, G.L., Derse, D., Misteli, T., and Franchini, G.  (2004)  HTLV-1-encoded p30^II is a post-transcriptional negative regulator of viral replication.  Nat. Med. 10: 197-201.
[Abstract]     [Full-text PDF article]

Princler, G.L., Julias, J.G., Hughes, S.H., and Derse, D.  (2003)  Roles of viral and cellular proteins in the expression of alternatively spliced HTLV-1 pX mRNAs.  Virology 317: 136-145.     [Abstract]     [Full-text PDF article]

Chung, H.K., Young, H.A., Goon, P.K., Heidecker, G., Princler, G.L., Shimozato, O., Taylor, G.P., Bangham, C.R., and Derse, D.  (2003)  Activation of interleukin-13 expression in T cells from HTLV-1-infected individuals and in chronically infected cell lines.  Blood 102: 4130-4136.     [Abstract]     [Full-text PDF article]

Hill, S.A., Lloyd, P.A., McDonald, S., Wykoff, J., and Derse, D.  (2003)  Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.  J. Infect. Dis. 188: 424-427.     [Abstract]     [Full-text PDF article]

Derse, D., and Heidecker, G.  (2003)  Virology. Forced entry--or does HTLV-I have the key?  Science 299: 1670-1671.     [Full-text PDF article]

Heidecker, G., Hill, S.A., Lloyd, P.A., and Derse, D.  (2002)  A novel protease processing site in the transframe protein of human T-cell leukemia virus type 1 PR76(gag-pro) defines the N terminus of RT.  J. Virol. 76: 13101-13105.
[Abstract]     [Full-text PDF article]

Derse, D., Hill, S.A., Lloyd, P.A., Chung, H.-k., and Morse, B.A.  (2001)  Examining human T-lymphotropic virus type 1 infection and replication by cell-free infection with recombinant virus vectors.  J. Virol. 75: 8461-8468.
[Abstract]     [Full-text PDF article]

Chung, H., and Derse, D.  (2001)  Binding sites for Rev and ASF/SF2 map to a 55-nucleotide purine-rich exonic element in equine infectious anemia virus RNA.  J. Biol. Chem. 276: 18960-18967.     [Abstract]     [Full-text PDF article]

Shuh, M., and Derse, D.  (2000)  Ternary complex factors and cofactors are essential for human T-cell leukemia virus type 1 tax transactivation of the serum response element.  J. Virol. 74: 11394-11397.     [Abstract]     [Full-text PDF article]

Hill, S.A., Shuh, M., and Derse, D.  (1999)  Comparisons of defective HTLV-I proviruses predict the mode of origin and coding potential of internally deleted genomes.  Virology 263: 273-281.     [Abstract]     [Full-text PDF article]

Shuh, M., Hill, S.A., and Derse, D.  (1999)  Defective and wild-type human T-cell leukemia virus type I proviruses: characterization of gene products and trans-interactions between proviruses.  Virology 262: 442-451.
[Abstract]     [Full-text PDF article]

Pettit, S.C., Sanchez, R., Smith, T., Wehbie, R., Derse, D., and Swanstrom, R.  (1998)  HIV type 1 protease inhibitors fail to inhibit HTLV-I Gag processing in infected cells.  AIDS Res. Hum. Retroviruses 14: 1007-1014.     [Abstract]